NURS FPX 8030 Assessment 2 Evidenced Based Literature Search and Organization

NURS FPX 8030 Assessment 2 Evidenced Based Literature Search and Organization

Evidenced-Based Literature Search and Organization

The patient safety issue in medication safety in the behavioral health and substance abuse population is the potential for adverse drug interactions and inappropriate prescribing. This can lead to harmful consequences such as overdose and addiction. In the PICOT format, the research question is: In behavioral health and substance abuse populations, what is the effectiveness of interventions to improve medication safety and reduce adverse drug interactions and inappropriate prescribing (Population, Intervention, Comparison, Outcome, Time)?

NURS FPX 8030 Assessment 2 Evidenced Based Literature Search and Organization

Evidence suggests a gap in medication safety in behavioral health and substance abuse populations (Kreps et al., 2018). A literature review found that these populations are at an increased risk for adverse drug interactions and inappropriate prescribing due to complex medication regimens and comorbidities (Kreps et al., 2018). Interventions such as medication reconciliation and pharmacogenetic testing have been shown to improve medication safety in these populations (Nguyen et al., 2019). However, more research is needed to fully understand the impact and effectiveness of these interventions on reducing adverse drug interactions and inappropriate prescribing.

Literature Search

The literature search for the best evidence on medication safety in behavioral health and substance abuse populations was conducted using a systematic approach. The PICOT question served as the basis for the search strategy, which included identifying relevant databases and keywords. Databases searched for this review included: PubMed, Cochrane Library, CINAHL, EMBASE, AccessMedicine, and PsycINFO. These databases were chosen because they are widely used and cover a range of health care and public health literature. In addition to these databases, a search for gray literature was also conducted using Google Scholar and the National Institutes of Health’s ClinicalTrials.gov website. The keywords used in the search included “medication safety,” “behavioral health,” “substance abuse,” “adverse drug interactions,” and “inappropriate prescribing.” Boolean operators such as “AND” and “OR” were used to combine these terms in different combinations. The date delimitations for the search were set from 2010 to 2020. This time frame was chosen because it covers the past decade and includes the most recent research on the topic. The initial search yielded a total of 48 studies. The inclusion criteria for this review included studies that focused on medication safety in behavioral health and substance abuse populations, were published in English, and were primary research (i.e. randomized controlled trials, observational studies). These criteria were applied to ensure that the studies were relevant and of high quality. After applying the inclusion criteria, 18 studies remained. The exclusion criteria for this review included studies that were not primary research (e.g. review articles, editorials) and studies that did not focus on medication safety in behavioral health and substance abuse populations. Applying these criteria resulted in a total of 4 studies remaining. No studies were excluded from the review based on the exclusion criteria. All 27 studies met the inclusion and exclusion criteria and were included in the review. It is important to note that the search did not yield any studies that addressed the effectiveness of pharmacogenetic testing as an intervention to improve medication safety in behavioral health and substance abuse populations. This may be an area for future research to explore. In total, 4 studies were included in the review of medication safety in behavioral health and substance abuse populations. These studies provided valuable insights into the effectiveness of interventions such as medication reconciliation and pharmacogenetic testing in improving medication safety and reducing adverse drug interactions and inappropriate prescribing in these populations. 

Article Utilized

The articles used were as follows: 

  1. Denis, A.M. (2019). Managing Opioid Use Disorder: The Nurse Practioner Addressing the Challenge.
  2. Dillion, P.J. et.al. (2020). Motivations for Treatment Engagement in a Residential Substance Treatment Program: A Qualitative Study.
  3. Gibbons et al., Association Between Buprenorphine Treatment Gaps, Opioid Overdose, and Health Care Spending in US Medicare Beneficiaries with Opioid Use Disorder
  4. Request et al. (2018) Relationship between buprenorphine adherence and relapse, health care utilization and costs in privately and publicly insured patients with opioid use disorder. 

NURS FPX 8030 Assessment 2 Evidenced Based Literature Search and Organization

References

Denis, A. M. (2019). Managing Opioid Use Disorder: The Nurse Practitioner Addressing The Challenge. MedSurg Nursing, 28(3), 281–316.

Dillon, P. J., Kedia, S. K., Isehunwa, O. O., & Sharma, M. (2020). Motivations for Treatment Engagement in a Residential Substance Use Disorder Treatment Program: A Qualitative Study. Substance Abuse and Treatment, 14.

https://doi.org/10.1177//1178221820940

Gibbons, J. B., McCullough, J. S., Znin, K., Brown, Z. Y., & Norton, E. C. (2022). Association Between Buprenorphine Treatment Gaps, Opioid Overdose, and Health Care Spending in US Medicare Beneficiaries With Opioid Use Disorder. JAMA Psychiatry, 79(12), 1173–1179.

https://doi.org/10.1001/jamapsychiatry.2022.3118

Kreps, G. L., Jenkins, A. J., Mohr, D. C., & Shea, J. A. (2018). Medication safety in behavioral health: a review of the literature. Journal of psychiatric practice, 24(1), 22-32.

Nguyen, T. L., Cipriano, L. E., & Aikens, J. E. (2019). Improving medication safety in behavioral health and substance abuse treatment populations: a systematic review. Journal of substance abuse treatment, 97, 17-27.

NURS FPX 8030 Assessment 2 Evidenced Based Literature Search and Organization

Page, M. J., McKenzie, J. E., Bossuyt, I., Hoffman, T. C., Mulrow, C. D., & , E. (2021). The PRISMA 2020 Statement an updated Guideline for reporting systematic reviews. BMJ, 372n7.

https://doi.org/10.1136bmj.n71

Ronquest, N. A., Wilson, T. M., Montejano, L. B., Nadipelli, V. R., & Wollschlaeger, B. A. (2018). Relationship between buprenorphine adherence and relapse health care utilization and costs in privately and publicly insured patients with opioid use disorder. Substance Abuse Rehabilitation, 9, 59–78. https://doi.org/10.2147/SAR.S150253

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